Home / Jonathan Fuller, Meta-Evidence and Therapeutic Skepticism

 

Evidence is mounting of systematic problems in medical research. Meta-research shows that therapeutic trials with negative findings often go unpublished, while trials that are published often fail to be replicated. I call these kinds of meta-research findings ‘meta-evidence’ because they are about medicine’s evidence base. Moreover, as I will argue these findings should be used as evidence in evaluating medical therapies, including in quantifying therapeutic effectiveness. My argument implies a critical stance towards therapeutic estimates derived from contemporary clinical research, a stance that I call ‘modern therapeutic skepticism’.

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